When it comes to liver cancer, many people will be scared of it, just because the name of “king of cancer” makes people think more of despair. According to statistics, the number of liver cancer deaths in China ranks second among malignant tumors, after lung cancer. Nevertheless, having liver cancer does not mean despair. Professor Chong Yutian pointed out that there are many means of liver cancer treatment, such as surgery (including hepatectomy and liver transplantation), vascular intervention (also known as TACE), local ablation therapy (including radiofrequency, microwave, freezing, anhydrous alcohol injection, etc.), radiotherapy, molecular targeted therapy, biological therapy, etc.; and for early stage liver cancer, there is more chance of radical resection. For early stage liver cancer, there is even a chance of radical resection. However, when there are multiple treatment options available for a disease, how do you choose? For example, for the same liver cancer, some may recommend surgical resection, some may recommend ablation therapy, and some may recommend interventional therapy. Although each treatment method may be effective, which option is the most suitable for this patient? This reporter experienced a joint multidisciplinary consultation for a liver cancer case at Lingnan Hospital of the Third Affiliated Hospital of Sun Yat-sen University: the patient was 52 years old and his liver cancer (with a large mass) was found during a physical examination. For him, he had the opportunity to undergo both surgical treatment, interventional treatment and even direct liver transplantation, but which treatment method was more suitable for him? Doctors from eight specialties, including infectious diseases, general surgery, liver transplantation, intervention, radiology, biotherapy center, pathology, and ultrasound, analyzed the patient’s situation from their respective treatment perspectives. Among them, the general surgeon pointed out that although there is a chance of resection for liver cancer, due to the large size of the mass and its location in the center of the liver, it would be difficult and risky to remove it surgically, and it may not be guaranteed to retain enough remaining liver tissue to maintain liver function. According to the liver transplantation doctors, if the patient receives liver transplantation, the patient is eligible for liver transplantation; if the patient does not receive liver transplantation, because the patient’s current liver function is still normal, other methods of treatment can be chosen. Of course, once other methods of treatment have failed, the patient still has the opportunity for a viable remedial liver transplant after a rigorous evaluation. The interventionalist suggested that the patient was eligible for interventional TACE treatment, and after the interventional treatment, when the tumor shrinks, the patient could fight for the chance of surgical resection. After a thorough analysis and discussion, the treatment plan was finally agreed upon: the tumor should be shrunk by interventional treatment first, and then surgical resection should be performed. Prof. Chong Yutian pointed out that the diagnosis and treatment of liver cancer involves many specialties, including hepatology, general surgery (or hepatobiliary surgery), liver transplantation, interventional medicine, radiology, biotherapy center, pathology, ultrasound, etc. The situation of each liver cancer patient is different, so experts from related disciplines can sit together to consult and discuss the patient’s condition to find the best treatment plan. Therefore, he suggested that liver cancer patients should listen to the opinions of doctors from different specialties (liver cancer related) before treatment. It is understood that the Third Affiliated Hospital of Sun Yat-sen University has formally established a multidisciplinary integrated liver cancer treatment team at Lingnan Hospital to conduct regular joint consultations to provide patients with reasonable and individualized best treatment plans. Regardless of the specialty in which the liver cancer patient is first diagnosed, if the first physician determines that the patient needs a consultation, he or she can propose a joint multidisciplinary consultation to the hospital after informing the patient and obtaining consent.