TCT with atypical squamous cells does not necessarily lead to cervical cancer, and it is not possible to determine how long it will take to develop into cervical cancer. The presence of atypical squamous cells on TCT indicates the presence of abnormal cells, but the cause and extent of the cellular changes cannot be determined and need to be clarified by further HPV examination. If the HPV test is negative, observation is sufficient and is usually not a big problem. If the patient is found to have high-risk HPV infection, then colposcopy should be continued and a biopsy should be taken under colposcopy for pathological examination. Those with cervical inflammation should be treated aggressively with local medication; those with cervical lesions should be treated accordingly depending on the extent of the lesion. As long as the patient’s pathology shows no cervical lesion, but HPV virus is positive and TCT is atypical squamous cells, regular review is needed to avoid progression to cervical cancer, but there is no clear clinical conclusion on how long it can develop into cancer. Since cervical cancer is a preventable and treatable disease, it is recommended that married women should be screened regularly for cervical cancer.