Percutaneous vertebral body kyphoplasty is developed on the basis of PVP, which is a new technique to relieve pain and improve the quality of life of patients by introducing an expandable balloon into the diseased vertebral body after full expansion to reposition the fractured vertebral body and form a cavity, and injecting bone cement to enhance the stiffness and strength of the vertebral body, rebuild the stability of the spine, and correct the kyphotic deformity. Surgical indications 1. intractable pain caused by osteoporotic vertebral compression fracture; 2. pain caused by vertebral destruction and compression fracture due to benign and malignant tumors of the vertebral body; 3. non-healing vertebral fracture or cystic change; 4. painful vertebral fracture with osteonecrosis. Contraindications to surgery (a) absolute contraindications 1. coagulation dysfunction; 2. osteomyelitis of the vertebral body; 3. allergy to PVP instruments or materials. (2) Relative contraindications 1. vertebral fracture line crossing the posterior edge of the vertebral body with bone destruction and incompleteness; 2. severe vertebral fracture with vertebral compression exceeding 75%; 3. severe heart disease, extreme weakness and inability to tolerate surgery; 4. fracture of the vertebral arch; 5. full force infection; 6. vertebral fracture combined with nerve injury; 7. more than 3 vertebral bodies at a time requiring treatment; 8. painless vertebral body Compression fracture. Complications and prevention 1. Transient fever: rare, mostly caused by inflammatory reaction due to heat production of cement polymerization. Treatment with non-steroidal anti-inflammatory drugs; 2. Spinal cord and nerve root compression and thermal injury caused by cement leakage: Intraoperative strengthening of fluoroscopy and injection of cement dough can be avoided; once it occurs, emergency surgery should be performed to remove it; 3. Spinal infection: Since high fever is generated when cement monomer and powder are polymerized, the chance of spinal infection is rare. The small, transient complication caused by PVP is 1%-3% in osteoporotic patients and up to 1% in patients with vertebral tumors. Severe, permanent complications are rare. 5. Hematoma with local bleeding: Most often seen in patients with multiple punctures or with bleeding and coagulopathy. Pay attention to the correction of coagulation function before surgery; 6. Rib fracture: mostly seen in patients with severe osteoporosis. It may be the result of thoracic extrusion during puncture; 7. Death: the cause of death is not clear, but the cause of pulmonary embolism caused by simultaneous treatment of multiple vertebrae cannot be excluded. It is recommended that PVP should not exceed 3 stages at a time.