The production and adequate supply of genetically recombinant human growth hormone (rhGH) has promoted clinical research on growth hormone treatment of various dwarfism diseases. So far, it has been confirmed that treatment with growth hormone is effective for dwarfism caused by the following diseases: 1. Growth hormone deficiency: According to a large number of domestic and foreign and long-term clinical efficacy observations, if the child starts treatment at an early age and the amount of growth hormone is sufficient, the treatment continues until puberty when the child no longer grows tall. The height of the child can completely reach the height of an adult.
2. Congenital ovarian insufficiency: Turner syndrome, if treated for short stature, the average adult height of the child is only 143 cm. If treated properly with growth hormone, the child’s height can be increased by 10-16 cm.
3. Short stature in children younger than gestational age: The cause of short stature is due to intrauterine growth retardation, and the weight at full-term birth is less than 2500 grams. About 15% of these children are born with persistent short stature. Recent clinical studies have shown that growth hormone can promote height growth in small for gestational age children with a 1-fold increase in growth rate and no side effects.
4. Chronic renal insufficiency-induced dwarfism: Studies have shown that children with growth retardation caused by this disease treated with growth hormone grow 3-6 cm faster each year than those who have not been treated with growth hormone.
5. Idiopathic dwarfism: The application of larger doses of growth hormone treatment can accelerate the growth rate of the child by one time.