Chronic transit constipation of the colon

Constipation is a very common symptom, not an independent disease it is a complex symptom caused by a variety of diseases. According to the epidemiological survey confirmed: constipation and gender, age, race, diet, occupation, geography and life and labor habits and other factors. According to domestic and foreign reports, the ratio of men and women 1:3. in constipation in the colon chronic transmission type constipation, in recent years there is a trend of increase, but its diagnosis, treatment and there is no mature experience. Clinically referred to as stubborn chronic constipation, including colon chronic transmission constipation, habitual constipation and outlet obstruction constipation three types. Colon chronic transmission type constipation is mostly manifested as unexplained difficulty in defecation, no sense of bowel movement or sense of bowel movement is obviously weakened, less than 2 times per week or days to dozens of days to defecate once, prolonged defecation time, each time the time of defecation in 30min ~ 2h. Patients have abdominal distension, but there is no abdominal pain and nausea and vomiting, loss of appetite. This type of patients for colon transmission test, the 5th day of the abdominal X-ray film still has 50% of the markers stay in the colon, resection of the colon to do the pathology, the intermuscular plexus and the extra-mucosal plexus ganglion cells and neuronal cells significantly reduced, more illustrative of this disease. Chronic transport constipation is mainly characterized by the weakness of the motility of the colon, which reduces the ability of the colon to transit feces. Regarding the mechanism of the occurrence of chronic transport type constipation, the purpose doctrine can be divided into two categories. First, colon wall ganglion lesions The enteric nervous system can regulate the motor function of the colon, so the colon nervous system may be involved in the formation of chronic transport type constipation. It was found that the reduction of neuronal cells in the colonic intermuscular plexus and the extramucosal plexus had a direct relationship to the development of patients with slow transmission. Second, the movement of the colon in addition to its own enteric nervous system, part of the intestinal kinetic peptide, such as: vasoactive intestinal peptide, 5-hydroxytryptophan, etc. on the movement of the colon also play a role in regulating. It is found that the intestinal hyperglycemic cells and 5-hydroxytryptamine cells are significantly reduced in people with slow-transmission constipation, and the secretion index (CSI) of the intestinal hyperglycemic cells and 5-hydroxytryptamine cells is also significantly reduced, which suggests that the reduction of the endocrine cells in the colon may be one of the reasons for the slowing down of the colonic motility and the cause of the constipation. The treatment of colon chronic transmission constipation 1, conservative treatment For patients with shorter onset time and milder symptoms, conservative treatment is advocated. (1) regulate dietary habits, high fiber diet, drink more water, so that the intestinal tract by mechanical or chemical stimulation to enhance intestinal peristalsis, to prevent fecal dryness; (2) increase the amount of activity, to promote intestinal peristalsis; (3) change the bad habits of defecation; (4) reduce the inhibition of intestinal peristalsis by alcohol and other medicines such as codeine, morphine, anticholinergic agents, iron and antidiarrheal agents, etc.; (5) reduce the mental burden. Long-term constipation patients with heavy mental burden, fear of constipation pain inhibit defecation. 2, surgical treatment colon chronic transmission constipation by conservative treatment for more than half a year, or more long time ineffective, the patient’s pain is large, can consider surgical treatment, surgical indications [6: (1) there is definite evidence of colonic atony; (2) no outlet obstruction; (3) the anal canal has enough tension; (4) clinically no obvious anxiety, worry and mental abnormality; (5) there is no diffuse intestinal motility disorders of clinical evidence: such as intestinal irritation, the anal canal is sufficient tension; (5) no diffuse intestinal motility disorders of clinical evidence: such as intestinal agitation, the intestinal tract of the patient’s body. evidence: e.g., irritable bowel syndrome. Experts believe that the slow transmission type of constipation of the colon is better with subtotal colectomy anastomosis of the cecum and rectum. After the operation, the bowel movements are mostly 2-3 times a day.