Stomach pain, nausea, vomiting and diarrhea are common clinical symptoms, which may be caused by food poisoning, food accumulation, acute gastroenteritis, cholera and para-cholera. 1. Food poisoning: food poisoning can lead to stomach pain, nausea, vomiting and diarrhea, which need to be treated according to the pathogen, and drugs such as montelukast, antibiotics, vitamin B6 and acid suppressants can be used; 2. Occurs in children, due to overeating, excessive food intake, can not transport the symptoms of discomfort, treatment can be applied to stomach and digestive enzymes to relieve symptoms; 3, acute gastroenteritis: the usual unclean diet, infection with viruses or overeating lead to acute gastroenteritis, epigastric pain, with nausea, vomiting, diarrhea symptoms. At this time, avoid eating cool food, pay attention to abdominal warmth, and if necessary, take oral haloperidol, flavopiridol with montelukast, vitamin B6, etc. under the guidance of a doctor to relieve symptoms. In addition, patients are prone to dehydration symptoms and should be rehydrated in time, they can drink warm saline or sugar saline, and serious cases need timely infusion; 4. Cholera and paracholera: Patients are contaminated with Vibrio cholerae from ingested food or water, causing acute diarrhea with symptoms such as stomach pain, nausea and vomiting, and need to be hospitalized after clear diagnosis.