Gout is a disease caused by the precipitation and deposition of uric acid crystals in the body as a result of high uric acid in the body over a long period of time. If uric acid crystals are deposited in the joints, acute gouty arthritis can be triggered, causing severe swelling and pain in the joints, and the patient may even feel “unbearable pain”. Acute attacks of gout can cause severe joint pain, if unbearable, you can take non-steroidal anti-inflammatory painkillers, such as celecoxib, etoricoxib, diclofenac sodium, etc.. These drugs can effectively relieve pain in a relatively short period of time, but attention needs to be paid to the cardiovascular and gastrointestinal adverse effects caused by the drugs. Colchicine can also be used to relieve joint pain caused by acute attacks of gout, but because of its high incidence of gastrointestinal adverse reactions, it is very easy for patients to discontinue the drug because they cannot tolerate it. Therefore, colchicine is currently considered first for patients in the acute phase of gout who have contraindications to the use of non-steroidal anti-inflammatory analgesic drugs. If the patient’s condition is severe, the joint pain is unbearable, and the conventional drug treatment is not effective, or if there are contraindications to the use of both NSAIDs and colchicine, short-term use of glucocorticoids can be considered to control the symptoms. In addition, patients in the acute stage of gout should drink a lot of water and urinate more to promote uric acid excretion, and prohibit drinking alcohol, eating seafood, animal offal and other foods. For joint pain caused by gout, no matter what kind of medication is used, it needs to be guided by a physician, and the use of pain medication is only part of the gout treatment, and cannot solve the problem at the root.