Regardless of the location of acute gout, rapid relief of joint swelling and pain is the main treatment principle, and currently the main anti-inflammatory drugs are used to relieve pain. During the acute attack of gout, anti-inflammatory and analgesic treatment is recommended as early as possible (usually within 24 hours), among which non-steroidal anti-inflammatory and analgesic drugs should be the first choice, such as etoricoxib, diclofenac sodium, celecoxib, loxoprofen sodium, etc., but attention should be paid to the cardiovascular and gastrointestinal adverse effects of drugs. Colchicine is also very commonly used in the acute phase of gout, but because of its high incidence of gastrointestinal adverse reactions and the fact that it can easily cause patients to stop taking it because they cannot tolerate it, colchicine is currently used for patients in the acute phase of gout who have contraindications to the use of nonsteroidal anti-inflammatory analgesics. If the patient’s condition is severe and conventional drug therapy is not effective, or if there are contraindications to the use of both NSAIDs and colchicine, short-term use of glucocorticoids can be considered to control symptoms. In addition, patients in the acute stage of gout should drink a lot of water and urinate more to promote uric acid excretion, and prohibit drinking alcohol, eating seafood, animal offal and other foods. For patients in the acute stage of gout, regardless of the above mentioned drugs, they need to visit the rheumatology department first and develop a treatment plan under the guidance of a doctor. While using it, you need to pay attention to the adverse drug reactions, regular follow-up and follow up the discomfort.