Adapalene is a retinoid compound used clinically in the skin treatment of acne vulgaris with acne, papules and pustules as the main manifestation. It is not readily decomposed in air and sunlight. Studies have not found phototoxicity or photosensitivity. However, the safety of using adapalene during repeated exposure to sunlight or UV radiation is not known. Excessive sunlight and UV exposure should be avoided when using this product.
Side effects of adapalene gel: The main one is skin irritation. If used in excess, it may produce significant redness, peeling or discomfort. It may recover after reducing the number of doses or discontinuing the medication. The most common adverse reactions to adapalene gel during the initial 2-4 weeks of treatment are mild to moderate erythema, dryness, scaling, itching, burning, or stinging. Rarely occurring adverse reactions include acne erythema, dermatitis and contact dermatitis, ocular puffiness, conjunctivitis, erythema, pruritus, skin discoloration, erythema and eczema. If the adverse reactions are severe, the number of doses should be reduced or the drug discontinued. Safety and efficacy have not been established in pediatric patients under 12 years of age and are contraindicated in those with hypersensitivity to the ingredients of this product. Do not use this product during pregnancy. If it is necessary to use this product in breastfeeding women, do not apply it to the chest. Do not apply this product to the eyes, mouth, nasal mucosa and other mucosal tissues. It should not be used on broken skin (cuts, abrasions) or on very severe (erosion wounds) acne. Do not use this product in conjunction with other vitamin A acids or other drugs with similar effects and cosmetics that cause acne and have a shrinking effect.