Most of the symptoms of advanced hepatocellular carcinoma are hepatic face and generalized depletion state, and at the same time, it will cause jaundice due to the damage of liver function, resulting in elevated glutamic and glutamic aminotransferase, often yellow sclera and skin, and this yellow staining is easy to appear such as itchy skin. Patients who are in the late stage or have reached the state of near death are very often in a drowsy state, mostly due to physical exertion and nutritional depletion, causing general weakness and drowsiness. Fluid accumulation in the abdominal cavity due to malnutrition causes increased intra-abdominal pressure and little or no urination. Some may have symptoms of gastrointestinal bleeding due to recurrent cirrhosis and liver injury, which may lead to recurrent constipation or blood in stool, or even vomiting blood. Therefore, for the symptoms of advanced liver cancer, nutritional support should be given in general, and the changes of vital signs also need to be observed.