Wang, a 43-year-old male, underwent craniotomy for a right frontotemporal subdural hematoma with brain herniation, and was left with a right frontotemporal parietal skull defect after surgery. Three months after the craniotomy, the patient came to our hospital again for skull repair surgery. Through computerized 3D titanium plate shaping, our department designed a titanium metal artificial skull to fit the patient’s original skull shape, and successfully repaired the skull and restored the patient’s skull shape. The right frontal-temporal parietal skull defect with an area of about 8×7 cm is shown in the upper left picture, and the right frontal-temporal parietal skull defect is repaired by titanium plate in the upper right picture, and the shape is similar to the patient’s previous skull shape.