Recently, when Sun Yat Sen Memorial Hospital (the second hospital affiliated to Sun Yat Sen University) conducted annual health checkups for more than 400 employees of a unit, two patients with advanced liver cancer were discovered. Liver experts reminded middle-aged white-collar workers, especially those with a history of hepatitis, that they need to undergo liver checkups every six months, as annual employee checkups sometimes fail to detect changes in their condition in time. It is understood that the patient who was found to have liver cancer this time had a long history of hepatitis B and no signs of liver cancer were found in the previous year’s physical examination. Professor Liu Chao from Sun Yat Sen Memorial Hospital Hepatobiliary Hospital introduced that some liver cancers are highly malignant and the tumor cells grow “exponentially”, and it only takes a few months from the appearance to the detection of liver imaging (ultrasound, CT, MRI, etc.). If these two patients could have undergone liver checkups six months ago, they could have been detected and treated early, and their prognosis would have been very different. Therefore, Prof. Chao Liu recommends that patients over 40 years of age with a history of hepatitis infection should insist on liver ultrasound and blood methemoglobin tests every six months to observe whether there are any abnormalities in the liver. If liver ultrasound reveals a mass or elevated blood methemoglobin, a hepatobiliary surgeon should be consulted immediately. Patients with chronic hepatitis should never relax and reduce the frequency of examination Prof. Chao Liu also introduced that among the advanced liver cancer patients with combined chronic hepatitis he treated, some of them had undergone liver physical examination every six months but relaxed their vigilance and gradually reduced the frequency of examination after no abnormality was found for many years in a row, and as a result, liver cancer was found only when symptoms appeared, which was too late. These include two cases of Chinese from Canada who had undergone liver checkups every six months for more than 10 years at Canadiana University and found liver cancer of about 12 cm in diameter more than a year after they stopped the checkups. It may take 10 to 30 years from hepatitis virus infection to the occurrence of liver cancer, which mostly passes through the cirrhosis stage, but some chronic hepatitis B can develop into liver cancer directly without cirrhosis. According to statistics, from 1991 to 2004, more than 600 cases of hepatocellular carcinoma were resected at Sun Yat Sen Memorial Hospital, with the age range of 10 to 78 years old, with an average age of 49.5 years old and a high incidence of 45 to 55 years old. Never use physical sensation as a sign of physical examination Professor Liu finally reminded that many patients infected with hepatitis B do not feel any discomfort. Moreover, according to clinical observation, hepatitis B patients do not show obvious symptoms during the slow development of cirrhosis and liver cancer. Therefore, physical sensation and disease manifestation are not indicators of hepatitis and liver cancer. If you do not undergo professional liver examination, you may be infected with hepatitis B and even develop cirrhosis and liver cancer without being detected. Liver cancer detected due to pain in the liver area is in most cases at an advanced stage and has a very low chance of long-term survival. Professor Liu says that liver pain is caused by the abnormal and rapid growth of the diseased liver stimulating the peritoneum and diaphragm. Liver pain occurs in different people with different feelings. More commonly, patients complain of pain in the right upper abdomen, but they also complain of low back pain and scapular pain. In fact, this is a radiating pain caused by the liver pressing on the diaphragm, so the pain in these areas can easily make patients mistake the liver pain for low back pain or scapular pain, and delay the treatment of the.