Amniotic fluid embolism, which is the killer of death declaring war on doctors, occurs without any signs and symptoms, blood pressure drops, respiratory failure, cardiac arrest, etc. in just a few minutes, occurring rapidly and with urgent resuscitation time. The reported incidence of amniotic fluid embolism varies widely, ranging from 1:5000 to 1:80000, with 70% occurring during labor and 30% after delivery. The mortality rate can be as high as 70%~80% if it occurs in full-term delivery. So how exactly can it be prevented? Amniotic fluid enters the maternal blood circulation mainly through the uterine incision. Trauma, premature rupture of membranes, emergency delivery, advanced age, allergy, obesity, multiple births, placenta praevia, stillbirth, giant baby, uterine rupture, cervical laceration, and fecal contamination of amniotic fluid are the high-risk factors for amniotic fluid embolism to target mothers-to-be. How to prevent amniotic fluid embolism? 1.Regular obstetric checkups, early detection of causative factors; 2.Mothers at risk of amniotic fluid embolism, follow medical advice, pay attention to predisposing factors and understand some basic prenatal knowledge in advance; 3.Mothers who have abnormal feelings during labor must express their feelings promptly and clearly, for example, chills, shortness of breath, difficulty in breathing, irritability, vomiting and other uncomfortable feelings. So that the medical staff can make timely treatment and rescue plan; 4, early detection of delayed amniotic fluid embolism, such as the emergence of bleeding from little to much and blood does not clot, the application of uterine contraction agents such as contractions still can not effectively stop bleeding, need to draw attention to; 5, if there are problems during labor, the mother and her family should listen to the doctor’s advice, do not delay to win the rescue time.