Radionuclide patch therapy is one of the earliest, most common and most mature treatment methods used in nuclear medicine. It has been applied in clinical practice for more than 40 years. Since this therapy is effective in treating certain diseases, it only works on diseased tissues and does not cause damage to normal tissues, is painless, easy to operate, convenient to treat, and has obvious cosmetic effects, it is easily accepted by patients, especially infants and children, and is widely used in clinical practice. The principle of the dressing treatment is to use radionuclides that emit beta rays, such as 32P (32 phosphorus), 90Sr (90 strontium) or 90Y (90 yttrium), adsorb them evenly on filter paper or silver foil, make special dressing devices according to the shape and size of the lesion, put the dressing devices firmly on the surface of the lesion, and carry out external irradiation treatment on superficial lesions. Some lesions are more sensitive to beta radiation, and after ionizing radiation, degenerative changes such as microvascular atrophy and occlusion occur, and some diseases are cured by local vascular permeability change, increase of white blood cells and phagocytosis after irradiation; proliferative lesions can be controlled by slowing down cell division after irradiation. Beta radiation therapy is mainly applied to the treatment of simple cutaneous hemangioma, cavernous cutaneous hemangioma, keloid, intractable eczema and limited neurodermatitis, etc. Most of them can achieve satisfactory results.