Most of the early stages of pancreatic cancer have no obvious symptoms and are usually not painful, but as the disease worsens, pancreatic cancer patients may become very painful, especially when the tumor invades the nerve plexus in the surrounding abdominal cavity, there may be constant and severe pain in the lower back. This pain is usually unbearable pain and requires oral pain medication to control the pain. In addition to pain, pancreatic cancer is likely to cause obstructive jaundice, resulting in yellowish staining of the skin and sclera, and in some cases, itching is more intense throughout the body. Pancreatic cancer often leads to obstruction of pancreatic juice and bile excretion, which may cause a series of digestive symptoms, such as loss of appetite, indigestion, diarrhea, constipation, nausea, vomiting, etc. If the tumor invades the duodenum, it may lead to obstruction and bleeding in the digestive tract. Therefore, if the pancreatic cancer is in advanced stage, the patient is still suffering.