Liver cancer includes primary liver cancer and metastatic liver cancer. Primary liver cancer, also known as hepatocellular carcinoma, is a common malignant tumor in China. Metastatic liver cancer is also called secondary liver cancer, and malignant tumors of many organs can metastasize to the liver. The examination of liver cancer can be divided into physical examination and auxiliary examination. Physical examination of primary liver cancer: 1. Most patients can see liver palm, spider nevus, facial capillary dilatation and other manifestations. 2.Patients with advanced hepatocellular carcinoma may show yellow staining of skin and pore membrane, which is often caused by hepatocellular damage or tumor compression of bile duct. 3.The right upper abdomen or epigastrium is bulging or limited fullness, and veins are seen in the abdominal wall. The liver is obviously enlarged, with nodularity, hardness and pressure pain, sometimes hepatic artery murmur can be heard; most patients have splenomegaly and positive ascites sign. Auxiliary examinations include laboratory tests and special examinations, and laboratory tests can be divided into routine blood tests, liver function and tumor marker tests. The most important tumor marker test is serum fetoprotein, whose normal value is lower than 20μg/L. If fetoprotein is >400μg/L, pregnancy, embryonic tumor and reproductive system tumor are excluded, and liver cancer can be clinically diagnosed. Special examinations are further divided into ultrasonography, CT, MRI, hepatic arteriography, nuclear scan examination and liver biopsy examination. It is not difficult to diagnose liver cancer when typical symptoms appear, but it is often not early stage. Imaging examinations such as ultrasound, CT, MRI and detection of methemoglobin can help early diagnosis.