What should I do if I find a small lung lesion on CT that is not clearly benign or malignant?

  Our new article published in the top international journal Journal of the American Medical Association (JAMA) shows that lung cancer, the number one cancer killer, is developing at a younger age. The incidence rate of lung cancer in China has increased by an average of 1.63% per year since 1988-2005. With the increase of people’s health awareness and the popularity of high-resolution spiral CT in medical checkups, the detection rate of small lung lesions, which we professionally call hairy glass shadow (ground glass shadow) GGO, is also increasing.  Of course, the most important question is, is this little guy detected by physical examination cancer? What should we do?  We say that there are two types of GGO, one is transient, that is, 1-2 months later, the CT will disappear on its own, mainly due to inflammatory disease, focal hemorrhage and focal edema. Persistent GGO, on the other hand, should be considered as a possible lung cancer. Of course, not all persistent GGO is lung cancer.  (1) What are the imaging signs of the “bad” and “malignant” GGO on CT films?  Our doctors mainly look for several points: diameter >8mm, bronchial air-containing sign, vacuolar sign, lobar sign, and burr sign. All of these points are signs that GGO is malignant.  (2) Who are the high-risk group for lung cancer? The following people should take GGO seriously!  Age >60 years, smoked >20 cigarettes/day, >30 years, quit smoking <10< span=""> years, previous history of malignant disease, etc. Non-smokers: secondhand smoke, coal smoke, lung disease (COPD, TB, etc.), family history of tumor, high or low estrogen level, early or late menopause (3) What should be done if GGO is found in the lung during physical examination?  This will require a professional evaluation by a thoracic surgeon. We will give you a professional opinion!  For GGO <0.4mm< span=""> just follow up routinely, the possibility of malignancy is very small!  For 0.4-0.8mm GGO, CT needs to be reviewed after 3 months, 6 months, and 12 months, and follow-up should be at least 3-5 years.  0.8mm-10mm, surgical resection needs to be considered.  (4) Is surgical resection painful? Is it risky?  Basically, minimally invasive surgery is used nowadays (as shown below), which is less invasive. According to my study experience in Europe and the United States, foreigners in Europe and the United States usually get out of bed the day after surgery. Chinese people are less fit, but they can usually be discharged on the 7th day after surgery. The risk of this type of surgery is still very, very, very small.  (5) In the unfortunate case of “GGO lung cancer”, can the surgery be curative?  According to the statistics I got during my study in Germany and the United States, the five-year survival rate (that is, the cure rate) after timely surgery for “GGO lung cancer” can be 95%-100%.  Last but not least, I wish you all good health! Happy!