Uric acid is the end product of purine metabolism in our body. The amount of uric acid produced and the amount of uric acid excreted in our normal human body are generally maintained in a certain balance, however, if too much uric acid is accumulated in our normal human body, it will lead to high uric acid. If too much uric acid is produced or not enough uric acid is excreted every day, it will cause uric acid to accumulate in the body of a normal person, resulting in metabolic disorders, and the accumulation over a long period of time will lead to high levels of uric acid in the blood, i.e. hyperuricemia.
Patients may not have any symptoms and discomfort at the beginning of the discovery or each person’s reaction is different, but they should not take it lightly and leave the disease they have behind them, living and eating without moderation, treating themselves as if they were the same as normal people and careless about everything, which will undoubtedly bring harm. In particular, patients should pay attention to the close relationship between hyperuricemia and gout, renal insufficiency, hypertension, atherosclerosis and many other diseases, which are mutually transforming. If no effort is made to improve the symptoms, the risk of developing gout and coronary heart disease and hypertension will increase. Liu Ruixia, Department of Health Care, Affiliated Hospital of Shandong University of Traditional Chinese Medicine
The dangers of hyperuricemia are summarized as follows.
1. Kidney dysfunction
If gout is not properly treated, long-term persistent hyperuricemia will cause excessive uric acid crystals to precipitate in the kidneys, resulting in gouty nephropathy, or kidney dysfunction.
2. Ischemic heart disease
The American Heart Association has listed gout as a risk factor for ischemic heart disease and as a promoter of atherosclerosis. If gout is not properly treated, persistent hyperuricemia will cause excessive uric acid crystals to be deposited in the coronary arteries, which, together with the hyperagglutination of platelets, will accelerate the progress of atherosclerosis.
3. Kidney stones
According to statistics, the chance of kidney stone for gout patients is about a thousand times of normal people; because the more uric acid in the urine, the more acidic the pH, the more likely to occur stones, so we must drink more water, take baking soda to prevent the occurrence of kidney stones.
4.Obesity
Our country because of the rapid economic growth, food enough, so more and more obese people; obesity will not only make the synthesis of uric acid hyperactive, resulting in hyperuricemia, but also will impede the excretion of uric acid, easy to cause gout, combined with hyperlipidemia, diabetes, etc.. The main reason is often overeating, so obese people should lose weight.
5, hyperlipidemia
Gout people are more often overeating, and more obese phenomenon, so a lot of combined hyperlipidemia, which has a very close relationship with the occurrence of atherosclerosis.
6.Diabetes
Oral glucose load test was conducted on gout patients, and it was found that 30-40% of them had “mild non-insulin-dependent” diabetes mellitus.
7. Hypertension
About half of the gout patients are combined with hypertension. In addition to the renal hypertension caused by renal dysfunction mentioned above, gout patients combined with obesity is also one of the reasons. Because the hypertension treatment medicine often uses the hypotensive diuretic, will inhibit the uric acid excretion, and makes the uric acid value rise, this point must pay attention to.
First, pay attention to control the diet. In the daily diet, pay attention to avoid eating some high purine food, such as pig liver, chicken tripe and other animal offal, crabs, shrimp and all kinds of sea fish, beef and mutton and other purine-rich meat should be eaten as little as possible; pay attention to drink more water to reduce the concentration of blood acid, promote uric acid excretion and prevent uric acid road stones; eat more root food, eat more fresh fruits and vegetables, mushrooms, nori should not be eaten in large quantities; patients must Prohibition of alcohol, especially the absolute prohibition of beer.
Second, pay attention to life conditioning. Patients with hyperuricemia should pay attention to excessive mental tension in daily life, pay attention to avoid staying up late as much as possible, develop regular living habits, quit drinking and smoking, and play outdoor sports appropriately. To pay attention to weight loss, not to let the weight is too overweight.
Third, we should pay attention to uric acid monitoring. Patients with hyperuricemia who have a family history of gout should pay attention to blood uric acid monitoring every other month to prevent the development of the disease. If combined with obesity, hypertension, hyperlipidemia and other metabolic diseases, patients should actively reduce uric acid while treating the comorbidities, and if necessary, carry out drug therapy.