1.Clinical manifestations Increased leucorrhea, vaginal contact bleeding, lower abdominal pain, lumbosacral pain, frequent urination, hematuria, etc. 2.Signs Early stage cervical cancer: local erosion, erythema, superficial ulcer or smooth without any neoplasm visible to the naked eye may appear on the cervix. Progressive cervical cancer: obvious neoplasm may appear, the original shape of the cervix may disappear, and the local cervical neoplasm may appear as erosion, cauliflower, ulcer or nodular neoplasm. 3.Laboratory examination Routine blood, liver and kidney function, routine urine, routine stool, HPVDNA test, CEA, CA125. 4.Imaging examination Chest X-ray, B-mode ultrasound of uterus and both kidneys or pelvic CT/MRI, bone ECT. 5.Exfoliative cytology examination Traditional Pap staining of cervical exfoliated cells: Grade 1, normal cells; Grade 2, benign changes, mostly inflammation; Grade 3, suspicious carcinoma, grade 4, highly suspicious carcinoma, probably in situ; grade 5, mostly invasive carcinoma. Basal cytology: compared with the traditional Pap smear technique, the sensitivity of detecting low-grade and high-grade lesions is increased by 10%-15%. 6.Histopathology Cervical biopsy, cervical canal scraping, conical hysterectomy. 7.Endoscopy Colposcopy, cystoscopy, proctoscopy