Clinical manifestations of primary hepatocellular carcinoma mainly include pain in the liver area, systemic and digestive symptoms, fever, paraneoplastic manifestations and signs such as ascites.
1. Pain in liver area: it is usually pain in the right upper abdomen or middle-upper abdomen, which is mainly due to the tension of liver envelope caused by tumor growth. Pain in other parts of the body is seldom caused by liver lesions.
2. Systemic and digestive symptoms: such as loss of appetite, abdominal distension, nausea, vomiting, diarrhea, etc. Patients with advanced hepatocellular carcinoma will develop malignant disease. Stubborn ascites and jaundice will appear when thrombosis occurs in portal vein or hepatic vein.
3. Fever: mostly 37.5～38℃, and antibiotics are mostly ineffective. Fever with effective antibiotic treatment is usually not related to hepatocellular carcinoma.
4. Paracancerous manifestations: including hypoglycemia, erythrocytosis, feminization, hypertrophic osteoarthropathy.
5. Physical signs: there may be hepatomegaly, jaundice or ascites, etc. However, it should be noted that primary hepatocellular carcinoma cannot be diagnosed conclusively when there are the above signs.
Primary liver cancer is a malignant tumor, if there are related risk factors and symptoms, one should go to regular hospitals for clear diagnosis in time to avoid delaying the condition.