Statistics show that about 15% of couples fail to have children normally within one year after marriage, and about 40% of these patients have male factors, or what we call male infertility patients. The most important concern for these patients is the treatment of male infertility. Many male infertility patients can’t wait to ask their doctor how to treat low sperm viability once they see the results of routine semen tests. How to treat high sperm malformation rate? How to treat oligospermia? In the workplace, we often hear patients complaining about why they have used so many drugs without any effect. To answer these questions, we have to start with the diagnosis of male infertility. The most important diagnostic basis for male infertility is, of course, the results of routine semen examination. The results of the routine semen examination allow us to assess the fertility of the patient, and based on the results of this examination we can make a diagnosis of weak spermatozoa, oligospermia, abnormal spermatozoa, and azoospermia. This test is also the most familiar test for male infertility patients. Some patients come to the hospital and ask for a routine semen test, and then get the results and find a doctor to prescribe medication. However, it is not enough for male infertility patients to just check the semen routine, because the semen routine test results can only tell us the level of male fertility, but does not suggest the cause of low fertility in male infertility patients, nor does it provide more basis for the development of treatment plans. As a result, some patients with male infertility have been treated repeatedly, but have been unable to achieve satisfactory results. In order to improve the therapeutic effect of such patients, it is usually also necessary to perform some specific tests to try to find the cause of abnormal sperm indicators. The following are some of the relevant tests that are currently carried out in the clinic: 1. Sperm membrane surface antibodies can detect the presence of immune factors in male infertility patients; 2. Seminal plasma fructose and glycosidase tests Seminal plasma fructose and glycosidase are markers of the seminal vesicle gland and epididymis respectively, and this test can determine the functional status of the accessory gland and the presence of obstruction of the vas deferens; 3. Sex hormone tests The sex hormone test can determine whether the patient has endocrine disorders; 4, seminal plasma elastase test and semen leukocyte staining elastase is a protein enzyme secreted by neutrophils in the lobulated nucleus during the inflammatory process, and is a marker of male genital tract inflammation. This test is important for patients with poor semen liquefaction; 6, seminal plasma lactate dehydrogenase test Seminal plasma lactate dehydrogenase test is a key enzyme for sperm motility, and this enzyme test can assist in determining sperm quality and predicting sperm fertilization ability; 7, acrosome enzyme test This test mainly assesses the fertilization ability of sperm; 8, chromosome and spermatogenic factor test The purpose of this test is to evaluate male infertility patients. The purpose of this test is to evaluate whether there are congenital factors in male infertility patients; 9, seminal plasma zinc test zinc, as a cofactor of more than 100 enzymes in the body, is an essential element related to human growth and development, and is closely related to the metabolic activities of the reproductive system, the detection of seminal plasma zinc has certain guiding significance for the treatment of male infertility. Of course, not all patients need to undergo all of the above mentioned tests, and the specific tests to be performed need to be individually arranged by the clinician based on his or her experience and the patient’s actual situation. After a comprehensive examination, some patients can find out the cause of the abnormal semen test and carry out the corresponding treatment for the cause, and the treatment will be more effective. In some cases, the cause cannot be identified after a comprehensive examination, so empirical treatment can only be performed. If the patient is still unable to conceive after appropriate treatment, treatment with assisted reproduction techniques such as artificial insemination and IVF should be considered.