Incidence of cervical cancer
Cervical cancer is one of the most common malignant tumors in women. There are about 500,000 new cases of cervical cancer worldwide each year, about 380,000 in Asia and 150,000 in China, and about 230,000 women die of cervical cancer worldwide each year, about 190,000 in Asia and about 80,000 in China. Cervical cancer is the second most common malignant tumor in women, but now there is a significant rise and younger trend in China. the number of HPV infection is rising and trending younger. The “death of a famous woman” has aroused the attention and importance of cervical cancer in China.
High risk factors of cervical cancer
1, persistent HPV infection.
2.Premature sexual life.
3.Smokers and drug addicts.
4.Persons with family history of cervical lesions, cervical cancer, endometrial cancer, vaginal cancer or vulvar cancer
5.sexual partners or sexual partners with multiple sexual partners
6.sexual partners with cervical cancer
7.People with HIV (AIDS virus) infection.
8.Persons with other STD (sexually transmitted diseases)
9.People who are receiving immunosuppressive therapy.
10.Low-income group.
HPV infection and cervical cancer
1. HPV infection, especially high-risk HPV, is clearly associated with the development of cervical cancer, and high-risk HPV infection is found in 99.7% of cervical cancers.2. HPV infection strongly predicts the possibility of squamous intraepithelial lesions (SIL).
3, Persistent infection with high-risk HPV types perpetuates and progresses CIN grade III.
4, The presence of HPV infection alone predicts the presence of disease.
5.HPV infection increases the relative risk of cervical cancer by 250 times.
Human papillomavirus (HPV)
1. There are more than 80 types of HPV about 35 types are associated with reproductive tract infections.
About 20 types are associated with cancer.
2. There are 13 high-risk HPV types associated with cervical cancer: 16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, 68.
3. The low-risk types associated with cervical cancer are: 6, 11, 40, 42, 43, 44.
Domestic and foreign medical authorities confirmed that
Cervical cancer is an infectious disease, a preventable disease, and the only cancer in the world that can be detected and cured at an early stage! The key to cervical cancer prevention and treatment is early screening.
Cervical cancer screening and early diagnosis and treatment guidelines
Screening target: Women who have been sexually active for more than three years or who are sexually active at the age of 21 or older.
Starting age: economically developed areas: 25-30 years old; economically less developed areas: 35-40 years old; high-risk groups: the starting age should be advanced accordingly.
Age of termination: Very low risk above 65 years old.
Screening interval: once a year, can be changed to 3 years for 2 consecutive normal cytology, can be extended to 5~8 years for 2 consecutive normal HPV and cytology, with screening focusing on high-risk groups rather than the number of screenings.
Follow-up target: cytology ≥ LSIL, histology ≥ CIN-1 “special occupation” population, HPV infected patients.