The treatment of thrombo-occlusive vasculitis is mainly conservative, taking anti-platelet drugs and vasodilators, and interventional therapy in severe cases. 1, general treatment: absolute prohibition of smoking; keep the foot clean and dry, prevent infection and trauma; prevent cold and keep warm, but not too hot, so as not to increase oxygen consumption and aggravate the disease. Avoid the application of vasoconstrictive drugs. Buerger exercise is recommended, the method is: the patient lies flat, elevate the affected limb 45 °, maintain 1 to 2 minutes, then both feet down next to the bed for 2-5 minutes, while both feet move around 10 times, then the affected limb flat rest for 2 minutes; each practice 10 times Buerger exercise, 3-5 times a day. 2.Medication: Medication can relieve the patient’s symptoms. Anti-platelet drugs, such as: aspirin, clopidogrel, etc. Vasodilator drugs, such as cilostazol, sargramostim, prostaglandin E1, etc. 3, interventional therapy: for more serious symptoms of thrombo-occlusive vasculitis, interventional therapy is required during the remission period of the disease. The purpose of interventional therapy is to dilate the narrowed or occluded blood vessels so that the peripheral tissue and cellular blood circulation can be improved. 4. Surgery: arterial thrombectomy, arterial bypass bridging, etc. The treatment principle of thrombo-occlusive vasculitis is to prevent the development of lesions, improve the blood supply of the affected limb, reduce the pain of the affected limb, and promote the healing of ulcers. In addition to exercise exercises for the affected limb and symptomatic support treatment with medication, the key to the treatment of thrombo-occlusive vasculitis is to insist on smoking cessation.