The United Nations World Health Organization has introduced the “ABC” principle for the prevention of sexually transmitted diseases, which also applies to the prevention of HPV infection and cervical cancer. ”A” (Abstinency) means “abstinence”, it is almost impossible to be completely abstinent, but we should try to be “abstinent”, everything needs to be in moderation. For adolescent girls, it is necessary to master the correct knowledge of physiology and moral norms, reasonable regulation, and avoid premature sexual activity. Anhui Provincial Hospital Obstetrics and Gynecology Department Zhao Weidong “B” (Befaithful) that is “faithful”, couples should be faithful to each other, avoid having multiple sexual partners or have sex with people who have multiple sexual partners. “C” (Condom), that is, “condom”, condoms for the prevention of sexually transmitted diseases, has a very important role. Proper condom use reduces the risk of HPV infection and also reduces the incidence of cervical cancer.