Liver cancer is a common malignant tumor with poor prognosis. One is hepatocellular liver cancer, which is the most common and accounts for about 90% of liver cancer, and the other is cholangiocarcinoma, which accounts for about 10%. Early detection and early treatment are important methods to improve survival time. At present, the general principle of hepatocellular carcinoma treatment is comprehensive treatment mainly based on surgery, including interventional therapy, radiofrequency ablation therapy, radiotherapy, targeted drug therapy, immunotherapy, Chinese herbal medicine, and treatment of underlying diseases, such as antiviral therapy. In addition, effective supportive therapy (liver protection, diuretic, biliary, albumin transfusion, etc.) is also a part of the comprehensive treatment. 1. What kind of people are prone to liver cancer? Liver cancer is known as the king of cancer, and once clinical symptoms appear, the prognosis is poor, so early detection of liver cancer is an important part of effective treatment. People who are prone to liver cancer often have the following characteristics (1) Have a history of hepatitis B or C, especially those who have hepatitis from birth through vertical transmission from mother to child. The risk of developing liver cancer is even higher if there are liver cancer patients in the immediate family. (2) Patients with alcoholic cirrhosis or schistosomal cirrhosis are at increased risk of cancer if combined with hepatitis. (3) Diet often contains carcinogenic substances: such as moldy peanuts, dried potatoes, dried radish, etc. Animal and vegetable oils should not be consumed after they have a harsh smell. (4) Other chronic liver diseases: such as autoimmune liver disease, primary biliary cirrhosis, fatty liver, biliary system diseases, etc. 2. Symptoms of early stage liver cancer: Strictly speaking, there are no clear symptoms of early stage liver cancer, which is the scary part of liver cancer. However, through careful questioning of patients, we have found some common symptoms that deserve attention. (1) Some symptoms similar to gastric disease: such as feeling of fullness, poor appetite, belching, nausea. (2) Diarrhea, indigestion, etc. (3) Weakness and weight loss. (4) Vague pain or swelling and discomfort in the liver area. (5) Bitterness in the mouth, fever, sweating, etc. (6) Yellow sclera, yellowing of urine. (7) Bleeding from the gums and nasal cavity (8) Hard masses in the upper right or upper middle abdomen. In short, early symptoms are often insidious and usually not easily detected. When there is obvious ascites, jaundice, gastrointestinal bleeding or tumor rupture, the disease usually develops to the middle and late stage. However, for the high-risk group, if the treatment is strengthened and regular checkups are conducted, combined with the early discomfort, a considerable number of people can be detected early and get better treatment. For those who have chronic hepatitis B or C, the following things can be done to detect liver cancer at an early stage and achieve better treatment results (1) Regular review of fetoprotein and ultrasound and other imaging tests. In patients with chronic hepatitis, the risk of liver cancer increases year by year after the age of 40 for men and 45 for women. Therefore, AFP and ultrasound should be done at least 1-2 times a year. Two points need to be emphasized here: firstly, negative AFP does not mean no liver cancer will be born; secondly, ultrasound examination should be performed in experienced liver cancer diagnosis and treatment center, otherwise it will be easily missed. (2) Regular checkups should be persistent. Liver cancer is generally a chronic process, so do not take it lightly if it has not been detected after 3-5 years of examination. It is very important to insist on regular checkups. (3) We should pay attention to some clinical symptoms of early liver cancer. Don’t think that it is a stomach disease, lack of rest, or too tired at work, etc., but go to hospital for proper examination in time when symptoms appear, especially when the symptoms persist or recur frequently.