Acute respiratory failure is a relatively common critical clinical syndrome that can easily lead to multi-organ failure if not treated in a timely manner. Before treating acute respiratory failure, it is important to go to a regular hospital to confirm the cause of the disease. If it is caused by a change in the objective environment, such as plateau reaction or drowning, it is necessary to disengage in time and administer the necessary oxygen, either artificially or with a ventilator. If it is caused by the patient’s pulmonary dysfunction, stroke or cerebral edema, respiratory stimulants can be used, and currently the more common ones are Lopressor and Niclosamide. Since these two drugs are central nervous system drugs, it is important to observe the patient’s drug reaction when using them. Once skin flushing, convulsions, increased body temperature and itching occur, the drug should be stopped within 20-30 minutes, especially for pregnant women and patients with a history of allergy, as well as patients with severe pulmonary heart disease. Of course acute respiratory failure can also be improved with rapid oxygenation using an oxygen concentrator to improve blood oxygenation. If the condition is more severe, high-flow oxygenators and extracorporeal membrane pulmonary oxygenation can be used. Acute respiratory failure is a serious condition that requires prompt medical treatment, but no doctor can guarantee that acute respiratory failure will be cured, so it is especially important to observe the patient’s pulse oxygen saturation and other vital signs with the right medicine.