Cervical cancer vaccine is not recommended after the age of 45 because the response to the vaccine is lighter at older age and the antibodies produced are lower and will disappear soon, so it will not have a preventive effect on HPV infection, so cervical cancer vaccine is basically not effective. At this time, cervical pre-cancer screening can be done regularly, that is, HPV test and cervical liquid-based cytology test. If both tests are normal, the test can be repeated after 3-5 years to detect HPV infection and precancerous lesions of the cervix in time, which is very useful to prevent the occurrence of cervical cancer.