A liver nodule detected by ultrasound or CT is only a preliminary result of an imaging study. Liver nodules are usually solid or cystic in nature and can be seen in many diseases and can be generally classified as benign or malignant nodules. Hepatic hemangiomas are probably the most common benign nodules found on physical examination. They typically appear as hyperechoic nodules on ultrasound. Cirrhotic nodules are also a common type of liver nodule. Patients with a history of hepatitis and long-term drinking habits can cause more damage to the liver due to inflammation or long-term chronic stimulation from alcohol. During these occurrences of liver damage, the liver undergoes continuous fibrosis to repair itself, and these fibrotic tissues gather to form the liver nodule changes characteristic of cirrhosis. In addition, focal nodular hyperplasia of the liver, inflammatory pseudotumors or hepatic adenomas are also benign nodular lesions of the liver that are not uncommon in clinical practice. Hepatic adenomas can also present as hepatic nodules and occur mainly in women who have been taking oral contraceptives for more than 5 years or in diabetic patients. The lesions are hypoechoic to hyperechoic in signal and the lesions are usually smaller than 8 cm, but may be larger than 15 cm. The most common of the malignant nodules is the hepatocellular carcinoma nodule. Generally speaking, most liver cancer nodules are in the middle to late stage when detected. The nodules are usually slightly larger in diameter, with irregular shape and unclear borders, and show infiltrative growth into the surrounding liver tissue. Some liver cancer nodules may have a pseudo-envelope with relatively clear boundaries. In the case of metastatic cancer that metastasizes to the liver from other sites, multiple nodules can often be seen. With the increase in obesity, diabetes and metabolic syndrome, it is not uncommon to find localized accumulation of fat in the liver that will resemble hepatic nodule-like changes in 10% of patients with fatty liver, usually occurring in the anteromedial segment of the left lobe. Treatment is usually not required. Liver nodules are only an imaging depiction of the phenomenon, and a professional physician is needed to determine and diagnose the specific disease.