1, osteoporosis is a systemic bone disease characterized by reduced bone mass and microstructural degeneration of bone tissue, which increases the brittleness of bone and makes it prone to fracture, it includes primary osteoporosis and secondary osteoporosis. 2.Primary osteoporosis refers to the bone degeneration that occurs with increasing age (or after menopause in women), including senile osteoporosis and postmenopausal osteoporosis in women. The underlying cause of osteoporosis in the elderly is that the role of new bone production is significantly weakened. 3, secondary osteoporosis refers to osteoporosis caused by certain diseases, drugs or other causes. For example: diabetes, hyper- or hypothyroidism, hyperparathyroidism, long-term bed rest, etc. Clinical manifestations of osteoporotic vertebral fractures: sudden onset of low back pain without or with only a history of minor trauma; may also be accompanied by shortening of height and hunchback deformity. The fracture of the thoracic and lumbar vertebrae can lead to reduced pulmonary function, abdominal distension, and reduced ability to eat, thereby reducing the patient’s quality of life and, in severe cases, endangering the patient’s life. Treatment of osteoporotic vertebral fractures: Objectives: 1. To relieve pain and improve activity impairment. 2. Correct the abnormal bone metabolism. 3. To improve the quality of bone and reduce the occurrence of fractures. Methods: 1. Prevent fractures caused by trauma. 2. Use anti-osteoporosis drugs and calcium under the guidance of doctors. 3.Vertebroplasty: It is a minimally invasive surgery in which a puncture needle is put into the diseased vertebrae with the assistance of a C-arm X-ray machine, and a balloon can be put into the diseased vertebrae first to expand them, and then specific materials are injected or specific materials are injected directly into the fractured vertebrae to achieve the purpose of relieving pain, stabilizing the fracture and allowing the patient to return to normal life as soon as possible. If the indications are properly selected, the treatment effect is satisfactory.