In the endocrine clinic, I often meet young people who come to see acne, which is not a major disease, but affects the aesthetics and is not easy to cure, often recurring. The causes of acne are complex, mainly related to high androgen levels, increased cortical secretion, abnormal keratinization of hair follicle cortical glands, and proliferation of Propionibacterium acnes. In some cases, it is also related to genetics, immunity, use of cosmetics, dietary stimulation and endocrine disorders. It is more common in adolescents of both sexes. The book “The Authentic Book of Surgery” says: “Lung wind, acne, rosacea three of the same species, acne belongs to the lung, rosacea belongs to the spleen, all are blood heat stagnation does not disperse.” Chinese medicine believes that from the diet is not disciplined, over-eating baking, drinking wine, thick and spicy products, heat and moisture, so that the Yang Ming stomach meridian dry knot, damp heat poison gas up the head and face can not be released, or irregular life, often stay up late, work pressure, liver qi stagnation, depression and fire within the onset. The pathological factors are dampness, heat, toxicity, depression, blood heat, and the key to the pathogenesis is depression and fire to close the depression, treatment to clear heat and detoxify, cool the blood and relieve depression. Prescription: Dandelion 15g, honeysuckle, aster, forsythia 10g each, wild chrysanthemum 15g, summer cress 20g, sorrel 30g, red peony 12g, rhubarb 6g, barley 30g, peppermint 10g, asclepias 10g, raw licorice 15g.