This is a problem faced and confused not only by doctors but also by patients and families. Glioma is the tumor with the most primary tumors in the skull. Due to its malignant nature, it is difficult to remove it cleanly during surgery, and despite the fact that many postoperative patients undergo radiotherapy and chemotherapy in the expectation of controlling or delaying its recurrence, the recurrence rate is still high for high-grade gliomas, which is a major problem in medicine. Solving such a problem is a matter for the world’s medical scientists. Let’s talk about how patients and families should approach and choose their treatment. Many patients with postoperative recurrence of glioma are suitable for secondary surgery and reoperation, allowing life extension, some insist on continuing radiotherapy or chemotherapy, and some give up treatment. Because each patient has different conditions and different family situations, it is completely understandable that there are such different choices. The author’s suggestion is that if one chooses a neurosurgical specialty hospital for a recurrent glioma, the cost is not very high, and people with some financial conditions, in order to prolong the patient’s life and satisfy his or her desire to live, they should choose to be treated with secondary surgery, as far as the current treatment status is concerned, other treatments are hardly as effective as secondary surgery.