Liver transplantation is an effective treatment for chronic liver disease and liver cancer, but it must be clear that it is not a cure-all, that it is not suitable for all patients, and that not all patients need it. Especially for liver cancer patients, the choice of liver transplantation is related to whether satisfactory treatment results can be achieved without increasing the physical and financial burden, not to mention the waste of valuable organ resources. We hope this reprinted article will help you to understand the choice of liver transplantation objectively and not to follow blindly or be afraid of it. Blindness and fear come from a lack of understanding and a lack of rigor in understanding the indications for treatment. It is like tailoring clothes to make them fashionable and to make the person wearing them beautiful because of them. This article also has some incomplete places, and there are also Fudan standards in China, which are not mentioned in the article. Although there are many standards, but they are combined with the level of medical care in each country or region, the characteristics of the human race disease, although still controversial, but can guide us to a greater extent to take a reasonable treatment method. It also provides a cornerstone for further research progress in related medicine, after all, we do not have today’s medical achievements since the day apes became human, and will not just stay the same.