The causes of osteoporosis are not yet completely clear, but the medical profession believes that they are related to the following factors: hormone regulation: there are as many as eight hormones related to osteoporosis, such as estrogen, parathyroid hormone, calcitonin, active vitamin D, thyroxine, androgens, corticosteroids, growth hormone, etc. The first four hormones are particularly important. For example, women who have had their ovaries removed or prematurely, are prone to osteoporosis due to reduced or no secretion of estrogen. This is because estrogen has the function of inhibiting bone resorption, enhancing osteoblast activity, inhibiting bone calcium melting out, and promoting bone reconstruction. Nutritional status: Nutritional factors such as calcium, phosphorus, protein, trace elements (such as fluorine, magnesium, zinc) deficiency is related to osteoporosis. In particular, calcium and phosphorus deficiencies are the main causes. Physical factors: Physical factors include whether or not to exercise regularly, sunlight exposure, and gravity loading factors. These are closely related to the development of osteoporosis. Diseases: Development of kidney disease, liver disease, diabetes, hypertension, hyperthyroidism, rheumatoid arthritis, rigid spondylitis, or certain cancers. Medications: People who take steroids, anticancer drugs, diuretics, anticoagulants, stomach medications or painkillers during the L period. Immune function: Immune function has a regulatory effect on bone reconstruction, so there is also a relationship between altered immune function and the occurrence of osteoporosis. Genetic factors: Genetic factors are also an important cause of osteoporosis, so it is necessary to ask patients with severe osteoporosis whether they have a family history of osteoporosis.