At present, with the aging of our population, prostate diseases have become more and more evident as a problem plaguing the lives of the majority of elderly men. In addition to the most common benign prostatic hyperplasia, prostate cancer has become a health killer for elderly men and has also become a focus of attention. In the United States, prostate cancer ranks second among deaths caused by malignant tumors. In China, the incidence of this tumor is also increasing year by year as the average age increases and testing methods such as blood PSA become widely available. However, due to its unique biology and anatomical location, the early symptoms of prostate cancer are not obvious, and patients who come to the clinic because of symptoms are already at an advanced stage, and prostate cancer and prostate hyperplasia can coexist, so some patients first notice the symptoms not of the prostate, but of its metastases (most commonly the bones), which gives rise to Mr. Gu’s case mentioned above. In addition to lymph node metastasis, the most common metastatic sites of prostate cancer are the bones of the whole body, mainly the pelvis, lumbar spine, sacrum, thoracic spine, and ribs, and most of these metastases are osteogenic changes, and there can be mixed osteolytic ones. Among them, the metastatic lesions in the thoracic and lumbar spine may compress the spinal nerves and cause the patients’ limb movement disorders. These bone metastases will eventually lead to pain in the corresponding parts of the bones and even pathological fractures. As we all know, tumors should be detected and treated early, however, for prostate cancer, a tumor that cannot be seen or felt outside the body, how can we detect it? First of all, we should pay attention to the symptoms of the primary lesion (prostate area), we cannot simply use the common prostate enlargement of the elderly to explain everything, the necessary examination is indispensable; secondly, we should pay more attention to the symptoms of metastatic foci, especially the multiple foci appearing on irregular bones such as pelvis and spine, we need to be highly alert to the possibility of bone metastasis of prostate cancer; finally, we should increase the efforts of census screening, for For elderly men, especially those over 50 years old, blood PSA and anorectal examination are necessary physical examination items. It is also important to note that once prostate cancer with bone metastases is detected, there is no need to panic much, although the lesions cannot be surgically eradicated at this time, but because of the biological characteristics of prostate cancer, its development is relatively slow and the current endocrine therapy is effective for most advanced prostate cancer and long-term survival has been reported. Even if endocrine therapy is poor for some patients, there are many integrated treatments available such as radiotherapy, chemotherapy and isotopes that can provide remission and stabilization, thus prolonging the survival of the patient.