In principle, nephrotic syndrome is a microscopic lesion, membranous nephropathy stage 1 with mild pathological changes, IgA nephropathy lee’s grade 3 or less, metabolic syndrome renal damage focal proliferative lesions, thylakoid proliferative nephritis, partial focal sclerosing nephritis and membranoproliferative nephritis can achieve clinical remission after clinical hormones, immunosuppression and with Chinese and Western medicine. The other types of chronic kidney disease are relatively difficult to relieve proteinuria, and it is difficult to reduce urine protein clinically. Generally speaking, the clinical results of proteinuria reduction in nephrotic syndrome are more satisfactory if the 24-hour urine protein quantification is 0.5-0.8 grams or less, but it is more difficult to completely eliminate clinical proteinuria. 2, chronic kidney disease proteinuria patients applying hormone and immunosuppressive therapy female patients can get pregnant, it is recommended to pay attention to chronic kidney disease pathology type serious, proteinuria reduction is not obvious, is taking hormone and immunosuppressive patients, pregnancy is not recommended, pregnancy indicators: stop using hormone and immunosuppressive therapy, the condition is stable for six months – a year patients can get pregnant, but need to pay attention to the pregnancy brought about by kidney pathology The risk of aggravation and the risk of disease recurrence. 3, diabetic nephropathy has appeared in the clinical phase of proteinuria and glomerular filtration rate decreased 60ml/min patients, the incidence of clinical endpoint events significantly increased, it is recommended to use a combination of Chinese and Western medicine clinical treatment to actively control the clinical phase of proteinuria, control blood pressure and lipids, reduce blood sugar fluctuations, improve the glomerular filtration rate as the principle. Diabetes itself can bring the risk of kidney function decline, it is recommended to actively early treatment, diabetic nephropathy clinical treatment is difficult, clinical remission is difficult, it is recommended to early interventional prevention and treatment. 4. For patients with purpura kidney, it is recommended that Chinese medicine treatment with evidence-based diagnosis and treatment may be more beneficial compared to children. 5. For patients with lupus kidney, active immunosuppressive treatment is recommended, combined with clinical treatment with Chinese and Western medicine in order to reduce the clinical risk caused by the decline of renal function. 6. For patients with membranous nephropathy combined with massive proteinuria, immunosuppressive therapy is required for clinical proteinuria greater than 8 grams, which may be clinically beneficial. Considering that the light manifestation of membranous nephropathy is a small amount of proteinuria, relatively speaking, the risk of renal function decline is small, only the combination of Chinese and Western medicine clinical treatment is recommended. 7, for patients with chronic renal failure need a comprehensive assessment of anemia, blood pressure, blood lipids, uric acid, cardiac function, whether the increase in volume load is obvious, metabolic acidosis correction, hyperkalemia clinical risk and other reasonable combination of Chinese and Western medicine clinical delay chronic renal failure into blood purification treatment interval as the central principle. 8, chronic kidney disease, whether it is proteinuria, kidney function decline basically no possibility of complete clinical cure, if you can go through clinical treatment, the disease remission, stable, the chance of recurrence is already very difficult, this point needs to be understood by every chronic kidney disease patients. Chronic kidney disease can really be cured at present, basically beyond the level of the entire modern medicine and Chinese and Western medicine combination of kidney disease clinical diagnosis and treatment. There is no miracle doctor for chronic kidney disease treatment, only down-to-earth diagnosis and treatment for patients with heart and soul.