Cranial defects are common after craniotomy for heavy craniocerebral trauma, cerebral hemorrhage, large cerebral infarction and other diseases, and postoperative patients are often susceptible to brain tissue damage because of the loss of cranial protection. So, for the damaged skull, what should be used to repair? Neurosurgery experts, now clinical mainly through the cranial bone repair material to repair the area of cranial defects, repair can not only restore the normal shape of the skull, but also to restore the brain function is important, so what material should be chosen to repair good? In cranial repair surgery, the repair material is an important factor affecting the repair effect. At present, the most commonly used cranial bone repair material is titanium mesh material, but the postoperative effect of this traditional metal material is not very satisfactory, and there are also disadvantages such as poor thermal insulation, poor tissue compatibility, easy to produce rejection reaction and interference with nuclear magnetic CT examination. At present, a more advanced repair material has appeared, that is, polyether ether ketone PEEK material, our clinic on the extensive use of this PEEK material for cranial bone repair surgery, and has been thousands of cases of patients with good repair, the material because of the various properties of the excellent, by the patients who have been repaired by the very good feedback. Professor Mu introduced, PEEK material is different from the traditional titanium mesh material, the material has very good tissue compatibility, basically will not produce a reaction; PEEK material is based on the patient’s skull CT data for three-dimensional shaping, highly restore the physiological structure of the skull; PEEK skull is embedded repair, after repairing the skull smooth appearance, will not produce like titanium mesh covered repair brought about by the cutting damage; PEEK material radiography is a very good material, the material has been very good for thousands of patients, and has been very good repair for thousands of patients because of the excellent performance of the material has been repaired by patients with good feedback. PEEK material has good ray transmittance, which does not affect various medical examinations after surgery; in addition, PEEK material is comparable to human skull in terms of elasticity, strength, heat insulation, stability, etc., which makes it a very ideal cranial bone repair material.