Before the treatment of male infertility must be clear: whether there are problems with the testes, epididymis, vas deferens, whether the semen condition of the male partner is normal, etc., and to clarify the cause of the disease and take different measures for different causes, it should also be noted that there are a large proportion of patients who cannot find out the cause of the disease, for idiopathic if less spermatozoa. For patients with abnormal female semen quality, the specific cause should be clarified and relevant tests such as seminal plasma biochemistry, endocrine, chromosomes, etc. should be done. For inflammation of testes, epididymis and seminal vesicle glands, anti-inflammatory drugs can be used; for low androgens, androgens can be supplemented, and for high lactogen, bromocriptine treatment can be given. Indications for surgery for male infertility are often obstruction of the vas deferens, such as ejaculatory duct obstruction, epididymal obstruction, varicocele, cryptorchidism, etc. For patients with very low sperm count, if medication and surgical treatment are ineffective, assisted reproduction techniques can be considered, including commonly used artificial insemination (artificial insemination by husband’s semen, artificial insemination by donor’s semen, etc.), various IVF techniques, etc. Of course, in the case of sperm density standards, some patients with weak sperm and immune infertility can use in vitro semen optimization technology, and then implement husband sperm artificial insemination. A special point to note is that IVF technology has now advanced to the point where “intrafollicular single sperm injection” can be performed, making it possible to obtain several fertilized eggs as long as there are several active sperm, thus making it possible to cure infertility in patients with very low sperm count. Similarly, the fertility rate for a single menstrual cycle of assisted reproductive technology pregnancy does not usually exceed 40%.