How to review and treat hepatitis B patients with normal liver function

First of all, it should be understood that normal liver function is not the same as a stable hepatitis B condition. In fact, patients with normal liver function who have chronic hepatitis B still have slowly progressing disease. The latest version of the guidelines for the prevention and treatment of slow hepatitis B states that antiviral therapy should not be administered to patients with viral replication but persistently normal or mildly elevated serum ALT levels unless the patient has severe liver fibrosis or cirrhosis. For patients with normal or mildly elevated liver function, especially for men over 40 years of age and women over 50 years of age, regular liver function, HBVDNA, ultrasound and, if necessary, liver puncture for hepatic histological evaluation of liver tissue are essential, and antiviral therapy is required if there is more severe liver fibrosis or cirrhosis.