What is dyslipidemia?

  Question 1: What is dyslipidemia?  Dyslipidemia, commonly referred to as hyperlipidemia, is an abnormality in the quality and quantity of plasma lipids, usually elevated plasma cholesterol and/or triglycerides, and also includes reduced HDL. It also includes abnormal lipoproteinemia. Some people have predominantly elevated triglycerides, some have predominantly elevated cholesterol, some have elevated both, and some have predominantly lower HDL cholesterol.  Question 2: What are the dangers of dyslipidemia?  Dyslipidemia can interact with other cardiovascular risk factors such as age, gender, smoking, obesity, diabetes and hypertension to cause atherosclerosis and increase the morbidity and mortality of cardiovascular disease. Therefore, prevention and treatment of dyslipidemia is important to improve quality of life and prolong life expectancy.  Question 3: Why do dyslipidemia occur?  Dyslipidemia is divided into primary and secondary dyslipidemia. Primary dyslipidemia accounts for the majority of them and the cause is unknown. It is thought to be the result of genetic defects or interaction with environmental factors. Environmental factors include poor dietary habits, physical inactivity, obesity, increasing age, and smoking and alcohol abuse. Secondary dyslipidemia can be caused by systemic diseases such as diabetes mellitus, hypothyroidism, liver and kidney disease, Cushing’s syndrome and SLE, or certain medications such as thiazide diuretics, beta-blockers, and long-term high-dose hormone use. Primary and secondary dyslipidemia can co-exist.  Question 4: What are the manifestations of dyslipidemia?  Most patients with dyslipidemia do not have any symptoms, but are detected during routine physical examinations. Therefore, the presence or absence of symptoms cannot be used to determine the presence or absence of dyslipidemia or the degree of dyslipidemia. Some patients will have yellow tumors, early onset corneal rings and lipidemic fundus changes. Severe hypercholesterolemia can sometimes present with wandering arthritis. Severe hypertriglyceridemia can cause acute pancreatitis.  Question 5: How should dyslipidemia be treated?  1. Lifestyle intervention is the primary and basic treatment for both primary and secondary dyslipidemia. Lifestyle interventions include dietary control, reducing the intake of cholesterol and saturated fatty acids such as animal oil, palm oil and cocoa butter in food, and supplementing with plant sterols and tolerable fiber. Increase regular physical activity and control weight. Quit smoking, limit salt, limit alcohol, and prohibit strong alcohol.  2.The treatment of secondary dyslipidemia needs to actively control the primary disease, such as diabetes, hypothyroidism, reduce or stop the use of drugs that can cause elevated blood lipids as much as possible, etc.  3.Regulated drug treatment. If lipids are still high after the above interventions, then drug therapy needs to be activated in time.  Question 6: How long do I need to take lipid-regulating drugs?  Lipid-regulating drugs can be stopped when the abnormalities are corrected, but long-term lifestyle interventions are still needed. If lipid abnormalities reappear after stopping lipid-regulating drugs, long-term or even lifelong medication is recommended. Monitoring of lipid levels, muscle enzymes, liver and kidney function, and blood count is required during the course of medication.