According to the statistics of the Ministry of Health, primary liver cancer (hepatocellular carcinoma) has risen to the second place of malignant tumors since the 1990s, second only to lung cancer in urban areas and second only to gastric cancer in rural areas. In recent years, there has been great progress in the diagnosis and treatment of liver cancer, which is briefly described as follows. Guo Zhifeng, Department of Medical Oncology, Chifeng Hospital 1. Early diagnosis Alpha-fetoprotein (AFP) is still the best marker for qualitative diagnosis of hepatocellular carcinoma, but the positivity rate is about 70%. The combined application of multiple hepatocellular carcinoma markers may help to improve the diagnosis, and the main advances are AFP heteroplasm, rocket alglucosidase, abnormal prothrombin and pyruvate kinase. The expression of oncogenes and anti-oncogenes, such as ras gene and p53 protein, in hepatocellular carcinoma is also under investigation.　　Ultrasound is still considered to be the method of choice for screening and follow-up localized diagnosis. With hepatic artery injection CO2 ultrasound, 88% of primary hepatocellular carcinoma shows hyperechoic changes, while 70% of metastatic hepatocellular carcinoma shows hypoechoic changes. The combination of heparin and cortisone for hepatocellular carcinoma also has a sensitizing effect, which provides a reference for clinical application. Electrochemical therapy, also known as direct current therapy, is performed by inserting platinum electrodes into the tumor through percutaneous puncture under ultrasound guidance. The mechanism is to alter the internal environment of tumor tissue survival through the ionizing effect of direct current, which causes metabolic disorders in tumor cells. Intra-tumor injection of anhydrous alcohol has been widely used, and this method is safe, simple and low cost. It is mainly used for tumor