In the winter, invite three or five friends to sit around the stove, eating steaming hot pot, drinking, is a great blessing in life. However, the happiness often lurks in the hidden worries. Hot pot eat more or incorrect method of consumption may cause damage to the oral mucosa, long-term eating this hot, spicy food is undoubtedly a strong stimulus to the oral mucosa. And for this stimulation, some people say it is “cool!” But in fact, it is a “cruel torture”. This “torture” has something to do with the occurrence of oral cancer, the reason for which lies in the unique pathophysiological characteristics of oral mucosa. Oral mucosa is a layer of epithelial tissue much thinner than skin, which is very tender and naturally intolerant of heat and spicy. At the same time, the oral mucosa has a strong regenerative capacity, once subjected to “cruel torture” by the “destruction”, will be through epithelial proliferation to try to repair the “destruction” of the place. Research has found that the most suitable temperature for people to eat in about 10 ~ 40 ℃, the oral cavity generally tolerated the highest temperature of 50 ~ 60 ℃. When you feel very hot, the temperature is more in the 70 ℃ or so. People who often eat hot food do not feel hot even at a very high temperature, but when exposed to hot food and hot drinks at about 75℃, the delicate oral and esophageal mucosa will be lightly burned, and the burned mucosal surface will be shed and renewed in time, and the cells will be rapidly proliferated, renewed and replenished, in which case, once the proliferation of cells is abnormally accelerated or mutated under adverse stimulation (such as spicy stimulation), carcinogenesis. In addition, because the mucosa will thicken under the continuous proliferation of thermal stimulation, the thickened mucosa will become more and more insensitive to thermal and spicy stimulation, so that it will be more and more not afraid of hot and spicy, the more not afraid to eat more hot and spicy, the more the oral mucosa will thicken, so the vicious circle. It is found that smoking, alcohol, chronic friction and eating hot and spicy food are one of the factors that cause oral white spots to become cancerous. The transformation of white spots into cancer is also closely related to whether the local physical and chemical stimulation continues. Many studies have shown that esophageal cancer, cardia cancer and oral cancer in some areas are related to the possibility of hot and spicy food. In this sense, some cancers of mucosal epithelium may be “hot” or “spicy”.