The mandibular lingual release approach for the treatment of oral cancer avoids facial incisions and helps to ensure the normal appearance of the patient. The oral cavity is cavity-shaped, and intraoral surgical operations are often restricted due to the small oral fissure. Therefore, except for early-stage oral cancer which can be operated directly in the oral cavity, most oral cancers require incision of the lower lip or mandible to fully reveal the surgical field and completely remove the tumor, but the patient’s face is left with obvious scars after surgery, which may also be accompanied by the complication of poor healing of the mandible, which may lead to poor occlusal function and obviously affect the patient’s normal social life and work. The principle is to adopt a new surgical approach introduced from abroad – lingual release approach to the mandible, through a cervical skin incision, lowering the tongue and mouth to the neck, with full exposure of the operative field and complete removal of the tumor. It avoids lower lip splitting, mandibular osteotomy or mandibular resection. Dr. Zhang’s treatment team started to use the mandibular lingual release approach for oral cancer in 2003 and treated 20 cases of oral cancer between December 2006. Among them, there were 8 cases of floor of mouth cancer, 6 cases of tongue cancer, 2 cases of tongue root cancer and 4 cases of other sites. There were 2 cases of early stage tumors, 10 cases of intermediate stage and 8 cases of advanced stage. The control group was 20 cases of oral cancer with lower lip or mandibular osteotomy in the same period. The results revealed that the 3-year local control rates were 76.2% and 64.9% in the study and control groups, respectively; the 3-year survival rates were 52.3% and 50.0%, respectively; and the complication rates were 40% and 30%, respectively. Preliminary results showed that the mandibular lingual release approach for oral cancer did not affect the tumor treatment outcome compared with the traditional lower lip split or mandibulotomy approach. It overcomes the disadvantages of restricted oral access and incomplete resection, and avoids the scar left on the face by the lower lip split. The patient’s face is free of scars and biting difficulties after surgery. The oral surgery approaches without lower lip cleft can be broadly categorized as the following: 1.Simple oral approach: it is only suitable for early T1/T2 tongue cancer and superficial T1 floor of mouth cancer, and the surgical defect can be closed directly without repair; however, it is not suitable for T3/T4 tongue cancer and invasive cancer of the floor of mouth. 2.Lateral pharyngeal incision approach: it is only suitable for tongue root and posterior pharyngeal wall cancer with narrow exposure, and generally not suitable for oral cancer surgery. 3.Lingual cap flap approach: the lower lip is lifted upward from the mandibular surface through bilateral submandibular incisions and is suitable for tumors of the anterior oral cavity, such as anterior floor of the mouth, tongue belly and lower gingival carcinoma. The incision is adequately exposed, but severing the chin nerve causes numbness of the lower lip and postoperative facial lymphedema is obvious. 4. Pull-down approach: Tumor is removed through the oral cavity (marginal mandibular resection can be performed at the same time), and the oral specimen is connected to the cervical clearance specimen from the neck in combination with a muscle incision at the floor of the mouth. It is suitable for T2 and part of T3 floor of mouth cancer and tongue cancer, but still mainly resects the tumor from the oral cavity, the disadvantage is that the exposure is more limited and the flap suture repair is difficult. 5.Lateral mandibular lingual release approach: reported by Stanley in 1984, developed from the pull-down approach. Through this approach, the tongue and submouth are lowered to the neck, avoiding the splitting of the lower lip, mandibular osteotomy or mandibular resection. Moreover, the surgical field is sufficiently exposed to achieve complete removal of the tumor.