Chronic nephritis has always been one of the high-risk pregnancy factors of most concern to clinicians. Pregnancy can significantly increase the burden on the kidneys, and chronic nephritis can lead to abnormalities in pregnancy that can endanger the health of the mother and child. Is pregnancy possible in patients with chronic nephritis? According to current studies, pregnant women without large amounts of proteinuria and swelling and with serum creatinine less than 123µmol/L tend to have successful pregnancies with relatively few complications and less chance of rapid progression of primary kidney disease. Of course, pregnancy is contraindicated in women with high proteinuria, severe swelling, and active disease, especially if they are on heavy hormone and immunosuppressive therapy. In patients with chronic nephritis with serum creatinine greater than 124µmol/L, the complications of pregnancy are significantly higher, the renal function of the pregnant woman often progresses rapidly and even endangers maternal life, and the risk of abnormal fetal development and preterm delivery is greatly increased, with a poor prognosis.