Hepatitis B treatment has always been a difficult problem for the medical community. We know that hepatitis B is a contagious disease, so how to treat hepatitis B has become a matter of concern. Faced with the overwhelming advertisements of special effects of hepatitis B treatment, and faced with being deceived time and again, hepatitis B patients are confused. So, how exactly is hepatitis B treated? What are the hepatitis B treatment methods? There is a lot of debate about hepatitis B treatment methods, but broadly speaking, they are still inseparable from the four main points. To grasp the timing, choose the right program, long-term persistence, life rigorous. The timing of hepatitis B treatment is the key: most people, when they know they are hepatitis B, do not care if they are in the immune tolerance period, they blindly seek hepatitis B treatment methods, hepatitis B antiviral, liver preservation, anti-fibrosis and so on together, hoping to cure hepatitis B as soon as possible, but the effect of hepatitis B treatment is often not as good as it should be, but to add to the burden of the family. Some even aggravate the condition, making hepatitis B treatment more difficult and the condition more difficult to control. Therefore, when it comes to specific hepatitis B treatment, how to grasp the timing of hepatitis B treatment is key. First: the timing of hepatitis B treatment When the transaminases are more than twice normal, it indicates that the human immune system is activated and begins the exclusion reaction with the hepatitis B virus, while the liver cells show inflammatory damage, which is the best time for hepatitis B antiviral treatment. The body’s immune system works together with antiviral drugs to fight the hepatitis B virus in order to achieve a more satisfactory antiviral effect. When you are not sure if you want antiviral treatment, it is recommended to have a liver puncture to be able to determine if there is a need for hepatitis B antiviral treatment. Second: choosing the right hepatitis B treatment plan How to choose a plan for hepatitis B treatment needs to be determined according to the patient’s physical condition. It is currently believed that chronic hepatitis B should be treated in a comprehensive manner: antiviral, immunomodulation, improvement of liver function and anti-fibrosis. How to effectively administer hepatitis B antiviral therapy is the key to whether hepatitis B can be cured or not. Hepatitis B antiviral therapy is currently applied to alpha interferon, nucleoside analogues and immunomodulators such as thymidine preparations, but the efficacy is not satisfactory, and the hepatitis B virus is difficult to be completely cleared after treatment, and the relapse rate is high. The main reason affecting the antiviral efficacy of hepatitis B is the difficulty of complete clearance of hepatitis B virus (HBV) covalent closed-loop DNA (cccDNA) and immune tolerance to HBV in human body. Therefore, antiviral with immunomodulation to break the immune tolerance plays a role in the clearance of hepatitis B virus. Hepatitis B virus mutation can also reduce the effectiveness of antiviral treatment during hepatitis B treatment. Hepatitis B virus mutation can cause immune escape, the virus is not easy to clear; at the same time, the virus mutation can cause drug resistance, both can reduce the efficacy of hepatitis B antiviral. Hepatitis B treatment how to prevent viral mutation makes many experts headache, so should choose the appropriate program to avoid the occurrence of mutation. In addition, chronic hepatitis B is a chronic liver disease, often accompanied by liver fibrosis, according to the degree of liver damage in patients, some people need to carry out anti-fibrosis treatment at the same time, in order to avoid the development of liver damage to cirrhosis. The third: hepatitis B treatment requires long-term adherence Some hepatitis B patients take medication for three or five months, feel the effect is not obvious, just stop or change medication, resulting in the rebound of the disease, midway through the private change of medication, stopping medication will also affect disease control, increasing drug resistance. The occurrence of drug resistance will lead to recurrence and deterioration of the disease, and also increase the risk of developing cirrhosis and liver cancer. Cross-resistance between drugs will also limit the choice of drugs for future treatment of hepatitis B patients, causing patients to fall into a vicious cycle of “drug resistance, drug change, drug resistance again”, which not only brings trouble to hepatitis B treatment and a heavy economic burden, but also undermines the confidence of hepatitis B patients in treatment. Therefore, hepatitis B treatment should listen to the advice of experts and insist on long-term treatment until the antiviral discontinuation criteria are reached. In the antiviral treatment, the condition should be monitored at all times, and drug resistance should be observed at all times to make drug adjustments or combination of drugs according to expert advice to prevent or reduce the rate of hepatitis B virus resistance and improve the antiviral effect. The actual fact is that sometimes it is necessary to change the medication in the middle of hepatitis B treatment. Fourth: Hepatitis B major third-positive patients should live a rigorous life Hepatitis B treatment should also pay attention to the details of life and do a good job of basic treatment. How hepatitis B treatment effect and hepatitis B patients living habits are inseparable. 1, pay attention to rest: hepatitis B patients can work, but not strenuous. Overexertion affects the immune function of the body, affecting the effect of hepatitis B treatment, and even easy to cause a relapse or aggravation of hepatitis B. 2, moderate exercise: appropriate to do some aerobic exercise, such as playing tai chi, walking, climbing, swimming, breathing exercises, etc., can keep the body hard, positive energy, to improve the body’s immunity, improve the hepatitis B treatment effect is beneficial. 3, diet and living: abstain from alcohol. Spicy, greasy food should not be eaten, do not sleep, and do not stay up late, keep a regular routine. Many processed foods contain preservatives and should be eaten sparingly or not, more fruits and vegetables can increase the intake of vitamins, which is beneficial to the body. 4, regular checkups: chronic hepatitis B patients should see their doctors regularly in addition to regular liver function checks. Laboratory results sometimes do not fully represent the current condition, the doctor’s personal examination and advice is very important, some patients with early cirrhosis or liver fibrosis, biochemical tests often do not detect any changes, and the doctor’s lookout will give you tips, easier to grasp the timing of hepatitis B treatment and follow-up treatment plan. 5, reduce drug damage: Hepatitis B patients are not to take drugs indiscriminately, especially in the period of hepatitis B treatment, many drugs can cause abnormal liver function indicators and liver damage, so a variety of drugs try to take drugs under the guidance of a specialist, read the instructions carefully before taking drugs. To prevent and reduce the occurrence of drug-related liver damage. 6, keep a happy mood: keep a happy mood, the impact on liver drainage and the body’s immunity is very obvious, some people in a cheerful mood some diseases are often not cured, while others in a depressed mood, all day sad face people, often a long time to cure. Hepatitis B treatment cannot expect miracles alone, but miracles happen in direct proportion to the state of mind. It is beneficial for hepatitis B patients to follow the principles of hepatitis B treatment. At present, it is difficult to completely cure chronic hepatitis B with the existing antiviral treatment for hepatitis B, but having a good hepatitis B treatment principle can be of great help to hepatitis B treatment. The goal of chronic hepatitis B treatment worldwide is basically: to maximize the long-term inhibition or elimination of hepatitis B virus, reduce hepatocyte inflammation necrosis and liver fibrosis, delay and stop disease progression, reduce and prevent liver decompensation, cirrhosis, liver cancer and its complications, thereby improving quality of life and prolonging survival.