Gout is caused by disorders of purine metabolism and/or reduced uric acid excretion, hyperuricemia (blood uric acid >420umol/L), and deposition of urate crystals leading to recurrent acute arthritis, gout stones, chronic arthritis and even disability, urinary stones and renal insufficiency or even uremia. Gout is often associated with metabolic syndrome, such as obesity, hyperlipidemia, diabetes, hypertension and atherosclerotic cardiovascular diseases, such as coronary heart disease and cerebral infarction. Therefore, gout is not only arthritis, but also can have a variety of complications or comorbidities. With the improvement of people’s living standard, the incidence of gout is getting higher and younger, and there are more and more gout patients in their teens, and if there is no timely intervention, many diseases will appear in the future. Therefore, the prevention and treatment of gout needs to be paid great attention! How to detect gout early The following groups of people should have regular blood uric acid tests to detect hyperuricemia in time to facilitate early detection and prevention of gout: ① Elderly people over 60 years old, regardless of male or female and whether they are obese or not. ②Middle-aged obese men and postmenopausal women. ③Patients with diabetes, hypertension, atherosclerosis, coronary heart disease and cerebrovascular disease. ④Patients with unexplained arthritis, especially those over middle age characterized by the onset of monoarthritis. ⑤ Patients with kidney stones, especially multiple kidney stones. Acute gouty arthritis is an acute painful swelling of the joints that occurs due to cold, exertion, alcoholism, high purine diet, infection, etc. It often occurs at night, with red, swollen, hot and painful joints within a few hours, and is usually relieved by itself in 1-2 weeks, with intermittent periods of peace. At the beginning, most of the joints involved are the metatarsophalangeal joints of the big toe and foot, but then it may involve several joints, such as the back of the foot, ankle, knee, wrist, fingers, etc. Gout medication principles Arthritis in the acute phase of the attack to anti-inflammatory, the choice of drugs are non-steroidal anti-inflammatory drugs, colchicine, glucocorticoids, while taking sodium bicarbonate to facilitate the excretion of uric acid dissolution. After the arthritis has been controlled, uric acid-lowering drugs must be added, otherwise, gout will recur, commonly used uric acid-lowering drugs are allopurinol tablets, benzbromarone, febuxostat. If there is no gouty arthritis attack but only hyperuricemia, a comprehensive consideration is needed to determine whether uric acid-lowering treatment is needed. If uric acid-lowering treatment is needed, the above anti-inflammatory drugs can be added at the same time to prevent acute attacks of arthritis if necessary. Patients with gout or hyperuricemia should pay attention to diet control, exercise, weight reduction, quit drinking and smoking (especially yellow wine, beer and liquor), drink more water to make the daily urine volume above 2000ml to promote uric acid excretion and prevent urinary tract stones; low purine diet, avoid eating animal offal, meat soup, seafood, sugary drinks, limit beef and mutton, pork and Encourage the consumption of low-fat or non-fat dairy products, fresh fruits and vegetables, poultry meat and eggs to supplement animal protein, and celery and cherries.