The onset of kidney disease may vary from one cause to another. More commonly, patients feel easily fatigued, swollen after exertion, back pain, back pain, hematuria, increased foam in urine, increased or decreased urine output at night, frequent, urgent and painful urination. In some patients, high blood pressure is first detected and further examination confirms the diagnosis of kidney disease. In other patients, prolonged fever, recurrent arthralgia or rash are diagnosed only after a long period of time. Some of the symptoms mentioned above are easily detected by patients and attract attention, such as hematuria, swelling, decreased urine, painful urination, etc., while some are often not taken seriously by patients, but may indeed hide serious kidney damage, for example, increased nocturia may indicate reduced kidney function, increased foam in urine indicates that the patient may have egg white urine, etc. Therefore, the key to timely detection of kidney disease is to pay attention to the above signs of kidney disease.