The most likely cause of oral burning is oral cancer. The most likely cause of oral burning is oral mucosal dryness syndrome, which is common in women in their 40s and 50s. Painful mucous membrane after eating and speaking. If there are swellings or large mucosal ulcers in the oral cavity, and the ulcers are deep and persistent, or even have cauliflower-like hyperplasia, surface erosion and bleeding, and there is a foul smell in the oral cavity, you should be alert and go to the hospital in time for examination and pathological examination to determine whether there is oral cancer.