Pediatric diarrhea is the most common gastrointestinal syndrome among infants and young children in China. As the weather gradually turns colder, diarrhea in children caused by cold and warmth, improper diet or allergies will again take advantage of the situation. Diarrhea is a gastrointestinal syndrome with multiple causes and factors, and is a clinical condition caused by abnormal absorption and secretion of intestinal water and electrolytes and accelerated excretion of intestinal contents. Diarrhea can be divided into two categories: infectious and non-infectious, and particular attention should be paid to the prevention and treatment of infectious diarrhea. Infant diarrhea is 80% caused by viruses, of which rotavirus is the main pathogen, and is prevalent in autumn and winter, hence the name “autumn diarrhea”, but the peak of the epidemic is from October to December. Of course, it can also be spread in other seasons. The main clinical symptoms are vomiting, diarrhea, and sometimes fever, cough and other respiratory symptoms, so it is often misdiagnosed as upper infection and must be closely monitored. Patients often excrete watery or egg-flake soup-like stools, without mucus and pus and blood, or yellow thin stools, paste-like stools, without fishy odor, general stool routine examination can be seen a small number of white blood cells. The duration of the disease is about a week. When the diagnosis of rotavirus-induced diarrhea in children is confirmed, parents should not be alarmed and can use some medications under the guidance of a doctor. Parents must be reminded that they should pay great attention to the principle of prevention, and that they should develop hygienic habits in children’s diet, utensils and personal hygiene in order to prevent the disease from entering through the mouth.