Gout is an acute and chronic inflammation and tissue damage caused by the deposition of uric acid salts in the bones and joints, kidneys and subcutaneous areas. Hyperuricemia is the basis for the occurrence of gout, which can be divided into two main categories according to the different causes: 1. Primary gout: i.e. gout caused by unexplained hyperuricemia, caused by a combination of environmental and genetic factors, with a certain degree of family heritability. Except for a very small number of cases caused by congenital purine metabolism enzyme defects, the rest are mostly related to high purine diet and often co-exist with obesity, hypertension, diabetes, coronary heart disease, etc. 2.Secondary gout: Gout attacks caused by secondary increase in blood uric acid caused by kidney disease leading to reduced uric acid excretion, certain drugs inhibiting uric acid excretion, blood system diseases, radiotherapy and other aspects leading to increased uric acid production. At present, with the improvement of material living standard, high purine diet has become one of the main causes of gout. Drinking alcohol, seafood, animal offal, beef and mutton, and sweet drinks are the main types of high purine diet. Long-term high purine diet can cause elevated blood uric acid and lead to hyperuricemia. If the blood uric acid level is elevated for a long time, the concentration of urate increases and crystals are formed and deposited in joints and kidneys, leading to gout attacks. However, it is important to note that elevated blood uric acid alone does not equal gout; gout must occur with the formation and deposition of urate crystals. In summary, there are many reasons that can cause an increase in blood uric acid in the body and lead to gout. For those whose blood uric acid index is higher than normal, they should promptly seek medical consultation to identify the cause and carry out treatment and intervention to avoid causing gout attacks.