Most of the ground glass nodules in the lungs are lung cancer (50-75%), and some are benign lung lesions. If the nodules appear to increase in size or number during close follow-up, they should be surgically removed and the prognosis of surgical excision is confirmed. Since ground glass density nodules may be benign lesions, and even lung cancer may be early and not combined with microvascular invasion, these can be resected without lobectomy, and local excision (peri-pulmonary field 1/3) or segmental excision (middle and inner 2/3 of the lung field) is sufficient. Thus, local resection raises the additional question of how to quickly localize and reduce operative time during surgery? CT-guided percutaneous intrapulmonary ground glass density nodule hook-and-wire localization is a minimally invasive technique for localizing nodules that uses a mammographic hook-and-wire to locate the target target. Its features include: simple and convenient operation; low incidence of bleeding and pneumothorax; and few systemic adverse effects. With the proficiency of the operation technique and the need for patient treatment and thoracic surgery, the second interventional ward of our hospital The comprehensive interventional ward was the first to carry out percutaneous CT-guided percutaneous intrapulmonary ground glass density nodule hook and wire localization in the province in early 2014. By the end of 2014, dozens of procedures have been successfully performed, with lesion diameters of 3mm-11mm and a 100% technical success rate. Except for one person who experienced mild discomfort in the back after the indwelling positioning needle, all patients did not experience other complications and were treated with surgical resection on the second day after the procedure, and the intraoperative location of the nodule was quickly located, greatly reducing the operative time. It has added energy to minimally invasive treatment and provided new hope for many thoracic surgeons and patients with tiny intrapulmonary nodules. The indications for intrapulmonary glass nodule hook and wire localization are relatively broad, but all intrapulmonary nodules with glass density can be effectively localized, which is convenient for intraoperative surgery. It is believed that with the improvement and development of instruments and techniques, CT-guided percutaneous intrapulmonary glass nodule hook-and-wire localization will bring benefits to more clinicians, be recognized by more patients, and become a force for standardized treatment of intrapulmonary glass nodules.